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Biosensing (Optical & Electrochemical Systems)
Developing high-sensitivity sensors that translate biological interactions into measurable signals. Our research focuses on leveraging optical and electrochemical transduction methods to detect pathogens, biomarkers, and chemical pollutants with extreme precision.
Biosensors are the critical interface between biology and electronic data. Our lab focuses on the design of highly selective biorecognition elements (such as antibodies, aptamers, or enzymes) and their integration with sophisticated transduction hardware.
Key Research Pillars:
- Optical Sensing: Utilizing Surface Plasmon Resonance (SPR), fluorescence, and colorimetric techniques. These methods allow for label-free, real-time monitoring of molecular binding events with high spatial resolution.
- Electrochemical Sensing: Developing sensors based on amperometry, voltammetry, and impedance spectroscopy. These are ideal for miniaturization and offer a robust, low-cost path for electronic integration into portable devices.
- Surface Functionalization: Innovating chemical techniques to modify sensor surfaces at the molecular level, ensuring high specificity and reducing "noise" from non-specific binding in complex samples like whole blood or saliva.
- Multi-Analyte Detection (Multiplexing): Engineering sensor arrays capable of detecting multiple targets simultaneously from a single droplet, providing a comprehensive "molecular snapshot" of a patient's health.
Our goal is to push the limits of detection (LoD) to the single-molecule level, enabling earlier intervention for diseases and more accurate environmental monitoring.